The Bianconeri have started the season as favourites to beat Liverpool in their first encounter of the season.
They are unbeaten in Serie A and they face a Liverpool side who are just six points behind leaders Juventus.
The two sides have faced each other five times this season.
It’s not the first time that the Bianconers have faced Liverpool, and it will not be the last.
Here is what to expect: 1.
Can we expect the same from the visitors?
After the 3-0 defeat at the Stadio Olimpico, the Biancini players will be aware that they need to make a few adjustments in the starting line-up to ensure that they can keep pace with the big boys.
Coach Stefano Pioli wants his team to be more aggressive in the second half, but he will be mindful of the fact that Liverpool are favourites to win.
Who will score?
While the home side will be aiming to start the match with three players on the bench, the Italian champions are keen to have more options.
The team is not afraid to go out on the pitch and play the ball.
This will be the most important factor in the match.
Who can they afford to lose?
Liverpool have already suffered a major blow after the dismissal of Roberto Firmino and have had to adapt to a new starting XI.
They will be looking to take the game to the Biancocelesti with the likes of Daniel Sturridge, Luis Suarez, James Milner and Philippe Coutinho all on the sidelines.
This is a team who has struggled in the last couple of seasons, and with Sturridge out for several weeks, they need all the help they can get.
What about Suarez?
Suarez has struggled to establish himself as a key player for the Biancolic squad this season, especially after the Uruguayan left for Barcelona.
In his absence, Milner has become the focal point of the attack and Coutinho has been the one to provide the goal threat.
Who is the key man in the midfield?
The team will look to use Firmin, Coutinho and Sturridge to provide their attacking options and Milner will be one of the main goalscorers for the visitors.
It is unlikely that Luis Suarez will be on the field for Milan’s game against Liverpool.
His hamstring injury means that he is unlikely to be available for the clash.
What will be Neymar’s contribution?
After a solid start to the season, the Brazilian superstar has been unable to find the net for the side.
His role will be crucial for the defence as he is a great finisher, but it will be important for the attacking side as well to keep him fit.
Who could Milan face in the return leg?
It is expected that Liverpool will be a very difficult team to beat in the first leg.
Milan have been in a very good form in recent months, scoring 15 goals in all competitions, and they have the strength to beat a team like Liverpool.
However, the home team is very good on the counter-attack and will be able to make the difference if they are able to find a breakthrough.
Who should Milan be wary of?
Liverpool are a great team with some of the best players in the world.
They have had some problems this season in the defence and on the attack, but the likes